How exactly they did this is unclear - probably at present it's in the realms of science fiction - but the resulting hybrid chromosomes are injected into a donor embryo. The two scientists decide to secretly 'cross the line' and create such a hybrid. The scientists are now trying to sell their idea of introducing human genes into the splicing program to the company employing them - the notion gets shut down: the company is more focused on profits and pleasing its shareholders than dealing with the moral issues human-animal hybrids would raise. We learn the scientists have created two animal hybrids - Fred and Ginger - a pair of amorphous blobs who can be harvested for proteins useful for drug manufacture. Their grungy attire and music tastes err to the former - a notion backed up by their desire to be interviewed by 'Wired' magazine. Whether this is purely for fame or to find cures remains unclear. We first meet the superstar scientist couple during the movie's first ten minutes and see their mutual drive to push boundaries. Instead, it felt like the film writers had taken a few good ideas and 'spliced' them together in a random way -exploring a few provocative notions before tailing off without drawing meaningful conclusions.

Splice is, in fact, an apt name for the film, but not for this reason. 'Splice' refers to the 'cutting' of DNA sections - DNA splicingThe film centres around two superstar scientists - Adrien Brody and Sarah Polley as Clive Nikolai and Elsa Cast - who secretly create an animal-human hybrid using this scientific method.

I'm scared of the dark, but I hid behind my hands just once during the whole hour and 44 minutes and that was from sheer embarrassment at the storyline. Not only that, but this horror of a horror film was far from scary. At least if it had, it would be based on a storyline which - although tiresome - is proven to work. Buy this film on DVD from Amazon UK or Amazon USAįrom watching the trailers for Splice, I thought the film centred on a genetic engineering experiment gone awry - mutants taking over the world and so on.

Cast of splice